Recent Publications

High-level expression of biologically active glycoprotein hormones in Pichia pastoris strains-selection of strain GS115, and not X-33, for the production of biologically active N-glycosylated (15)N-labeled phCG

Glycoconj J (2008).



Translational Fusion of Two {beta}-Subunits of Human Chorionic Gonadotropin Results in Production of a Novel Antagonist of the Hormone

Endocrinology 148 (8), 3977 (2007)

Insights into male germ cell apoptosis due to depletion of gonadotropins caused by GnRH antagonists.

Apoptosis 12 (6), 1085 (2007)

Single chain human chorionic gonadotropin, hCGa: Effects of mutations in the a subunit on structure and bioactivity.

Glycoconjugate Journal 24 (1), 97 (2007)




Blanchard, V. Gadkari, R.A. George, AV. Roy, S. Gerwig, GJ. Leeflang, BR.

Dighe, RR. Boelens, R. Kamerling, JP.

Pareek TK, Joshi AR, Sanyal A, & Dighe RR

Roy S, Setlur S, Gadkari RA, Krishnamurthy HN, Dighe RR

Setlur, SR. Dighe, RR.

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The antigen binding sites of various hCG monoclonal antibodies show homology to different domains of LH receptor

Molecular and Cellular Endocrinology 260, 23 (2007).

Gadkari, R.A., Sandhya, S., Sowdhamini, R., and Dighe, R.R.

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Characterization of the N-linked oligosaccharides from human chorionic gonadotropin expressed in the methylotrophic yeast Pichia pastoris

Glycoconj J 24 (1), 33 (2007).

Blanchard, V., Gadkari, R.A., Gerwig, G.J., Leeflang, B.R., Dighe, R.R., and Kamerling, J.P.

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Expression of apoptotic genes in testicular germ cells and their modulation by luteinizing hormone

The Journal of Steroid Biochemistry and Molecular Biology 101 (1), 22 (2006).

Joshi, A.R. and R.R. Dighe

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Identification of a heterodimer-specific epitope present in human chorionic gonadotrophin (hCG) using a monoclonal antibody that can distinguish between hCG and human LH.

J Mol Endocrinol 34 (3), 879 (2005).

Gadkari RA, Roy S, Rekha N, Srinivasan N, & Dighe RR

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Click here for complete list of publication

Prof. Rajan R. Dighes


Structure function analysis lab

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