Annapoorni Rangarajan’s lab

MRDG Dept., Indian Institute of Science


Sundararaman A, Amirtham U, Rangarajan A. (2016). Calcium-Oxidant Signaling Network Regulates AMPK Activation Upon Matrix-deprivation. J Biol Chem. 2016 Jul 8; 291(28):14410-29.


Pulakkat S, Balaji SA, Rangarajan A, Raichur AM (2016). Surface Engineered Protein Nanoparticles With Hyaluronic Acid Based Multilayers For Targeted Delivery Of Anticancer Agents. ACS Appl. Mater. Interfaces, 2016, 8 (36), pp 23437–23449.


Balachander GM, Balaji SA, Rangarajan A *, Chatterjee K *. (2015). Enhanced Metastatic Potential in a 3D Tissue Scaffold toward a Comprehensive in vitro Model for Breast Cancer Metastasis. ACS Appl. Mater. Interfaces, 7 (50), 27810-27822, Dec 8 .


Dubey A, Rangarajan A, Pal D*, Atreya HS *. (2015). Chemical Shifts to Metabolic Pathways: Identifying Metabolic Pathways Directly from a Single 2D NMR Spectrum. Anal. Chem., 2015, 87 (24), pp 12197–12205,


Hindupur, S.K., Balaji, S.A., Saxena, M., Pandey, S., Sravan, G.S., Heda, N., Kumar, M.V., Mukherjee, G., Dey, D., and Rangarajan, A. (2014). Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells. Breast Cancer Research: BCR 16, 420-420.


Maliyakkal, N., Beeran, A.A., Balaji, S.A., Udupa, N., Pai, S.R., and Rangarajan, A. (2014). Effects of Withania somnifera and Tinospora cordifolia extracts on the side population phenotype of human epithelial cancer cells toward targeting multidrug resistance in cancer. Integrative Cancer Therapies, 1534735414564423.


Mittal, S., Sharma, A., Balaji, S.A., Gowda, M.C., Dighe, R.R., Kumar, R.V., and Rangarajan, A. (2014). Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: Novel therapeutic strategy for aggressive breast cancers. Molecular Cancer Therapeutics 13, 3198-3209.


Paranjape, A.N., Balaji, S.A., Mandal, T., Krushik, E.V., Nagaraj, P., Mukherjee, G., and Rangarajan, A. (2014). Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog. BMC Cancer 14, 785.


Mittal, S., Kumar, R.V., and Rangarajan, A. (2012). Cooperation of Notch and RAS/MAPK pathway leads to poor outcome in breast cancer patients. Molecular Cancer Research 72, 2149-2149.


Paranjape, A., Mandal, T., Mukherjee, G., Kumar, M., Sengupta, K., and Rangarajan, A. (2012). Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties. Oncogene 31, 1896-1909.


Sharma A, Paranjape AN, Rangarajan A, Dighe RR. A monoclonal antibody against human Notch1 ligand-binding domain depletes subpopulation of putative breast cancer stem-like cells (2012). Mol Cancer Ther. Jan;11(1):77-86.


Saxena, M., Stephens, M.A., Pathak, H., and Rangarajan, A. (2011). Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters. Cell Death & Disease 2, e179.


Dey, D., Saxena, M., Paranjape, A.N., Krishnan, V., Giraddi, R., Kumar, M.V., Mukherjee, G., and Rangarajan, A. (2009). Phenotypic and functional characterization of human mammary stem/progenitor cells in long term culture. PLoS One 4, e5329.


Kumar, S.H., and Rangarajan, A. (2009). Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation. Journal of Virology 83, 8565-8574.


Mittal, S., Subramanyam, D., Dey, D., Kumar, R.V., and Rangarajan, A. (2009). Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis. Molecular Cancer 8, 128.

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