2010 onwards

Santosh V, Arivazhagan A, Sreekanthreddy P, Srinivasan H, Thota B, Srividya MR, Vrinda M, Sridevi S, Shailaja BC, Samuel C, Prasanna KV, Thennarasu K, Balasubramaniam A, Chandramouli BA, Hegde AS, Somasundaram K, Kondaiah P* and Rao MRS: Grade specific expression of IGFBP-2, -3 and -5 in astrocytomas: IGFBP-3 emerges as a strong predictor of survival in patients with newly diagnosed glioblastoma. Cancer Epidemiol. Biomarker & Prev. 19(6):1399-1409, 2010. 2010 PMID: 20501753

Sreekanthreddy P, Srinivasan H, Sridevi S, Vrinda M , Arivazhagan A, Balasubramaniam A, Hegde AS, Chandramouli BA, Santosh V, Rao MRS, Kondaiah P and Somasundaram K: Identification of potential serum biomarkers of glioblastoma: Serum osteopontin levels correlate with poor prognosis. Cancer Epidemiol. Biomarker & Prev. 19(6): 1409-1422, 2010.PMID: 20530493

Polisetty N, Agarwal P, Khan I, Kondaiah P, Sangwan V, Vemuganti G. Gene Expression Profile of Epithelial cells and Mesenchymal cells derived from Limbal Explant Culture. Mol. Vis. 16: 1227-1240, 2010.PMID: 20664697

Ladda J, Donakonda S, Agrawal S , Thota B, Srividya MR, Sridevi S, Arivazhagan A, Thennarasu K, Balasubramaniam A, Chandramouli BA, Hegde AS, Kondaiah P, Somasundaram K, Santosh V and Rao MRS: Glioblastoma specific protein interaction network identifies PP1A and CSK21 as connecting molecules between cell cycle associated genes. Cancer Res. 70(16):6437-47, 2010. .PMID: 20663907

Prasad P, Khan I, Sasmal PK, Koley D, Kondaiah P and Chakravarty AR. Planar triazinium cations from VO(2+)-assisted ring cyclizations: a remarkably efficient thiazole species for nuclear staining, PDT and anaerobic photocleavage of DNA. Chem Commun (Camb). 47(13):3954-6. 2011.PMID:21336383

Biswas J, Mishra SK, Kondaiah P, Bhattacharya S. Syntheses, Transfection Efficacy and Cell Toxicity Properties of Novel Cholesterol-based Gemini Lipids having Hydroxyethyl Head group. Org Biomol Chem. 12:4600-13 2011.PMID: 21537498

Khan I, Agarwal P, Thangjam GS, Radhesh R, Rao SG and Kondaiah P*. Role of TGF-beta and BMP7 in the pathogenesis of oral submucous fibrosis. Growth Factors,29(4):119-27.2011.PMID: 21591998

Ravanan P, Singh SK, Rao GSRS and Kondaiah P*.: Growth inhibitory, apoptotic, anti-inflammatory and pro-differentiative activities displayed by a novel modified triterpenoid, Cyano enone of methyl boswellates (CEMB). J. Biosciences. 36(2):297-307.2011.PMID: 21654084

Ravanan P, Sano R, Priti T, Ogasawara S, Matsuzawa S, Cuddy M, Singh SK, Rao GSRS, Kondaiah P and Reed JC: Synthetic Triterpenoid Cyano Enone of Methyl Boswellate (CEMB) activates intrinsic, extrinsic & endoplasmic reticulum stress cell death pathways in tumor cell lines. Mol. Cancer Therap. 10(9):1635-43, 2011. PMID: 21746806

Jagannathan L, Chaturvedi M, Satish B, Satish KS, Desai A, Subbakrishna DK, Satishchandra P, Pitchappan R, Balakrishnan K, Kondaiah P*, Ravi V*: HLA-B*57 and gender influence the occurrence of Tuberculosis in HIVinfected people of South India. Clinical and Developmental Immunolog y, 2011:549023, Epub Aug 25 2011.PMID:21876708

Muñoz-Úbeda M, Misra SK, Barrán-Berdón AL, Aicart-Ramos C, Sierra MB, Biswas J, Kondaiah P, Junquera E, Bhattacharya S, Aicart E: Why Is Less Cationic Lipid Required To Prepare Lipoplexes from Plasmid DNA than Linear DNA in Gene Therapy? J Am Chem Soc. 133(45):18014-7; 2011.PMID: 21985329

Arivazhagan A, Kumar DM, Sagar V, Patric IR, Sridevi S, Thota B, Srividya MR, Prasanna K, Thennarasu K, Mondal N, Hegde AS, Chandramouli BA, Santosh V, Rao MR, Kondaiah P, Somasundaram K: Higher Topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving Temozolomide chemotherapy: Identification of temozolomide as a TOP2A inhibitor. J Neuro Oncol. 107(2):289-97, 2012. PMID:22102081

Misra SK, Kondaiah P, Bhattacharya S, Rao CN. Graphene as a Nanocarrier for Tamoxifen Induces Apoptosis in Transformed Cancer Cell Lines of Different Origins. Small. 8(1):131-43. PMID: 22102595

Basu U, Khan I, Hussain A, Kondaiah P* and Chakravarty AR*. Photodynamic Effect in near-IR Light by a Remarkably Photocytotoxic Iron(III) Cellular Imaging Agent. Angew Chem Int Ed Engl. 51(11):2658-61. 2012. PMID:22290597

Priyadarsini RV, Kumar N, Khan I, Thiyagarajan P, Kondaiah P and Nagini S. Gene Expression signature of DMBA-induced hamster buccal carcinomas: Modulation by chlorophyllin and ellagic acid. PLoS One 7 (4) e34628 April 2012.PMID: 22485181

Banerjee S, Prasad P, Hussain A, Khan I, Kondaiah P*, Chakravarty AR*. Remarkable photocytotoxicity of curcumin in HeLa cells in visible light and arresting its degradation on oxovanadium(iv) complex formation Chem Commun (Camb).. 48(62):7702-4. 2012.PMID: 22751487

Naz S, Ranganathan P, Bodapati P, Shastry AH, Mishra LN, Kondaiah P*. Regulation of S100A2 Expression by Transforming Growth Factor-? induced MEK/ERK Signaling and its role in Cell Migration/Invasion. Biochem J. 447(1):81-91 2012. PMID: 22747445

Muralikrishna A, Venkatesh BC, Padmavathi V, Padmaja A, Kondaiah P, Krishna NS. Synthesis, antimicrobial and cytotoxic activities of sulfone linked bis heterocycles. Eur J Med Chem.. 54:605-14, 2012.PMID:22748281

Basu U, Khan I, Koley D, Saha S, Kondaiah P, Chakravarty AR. Nuclear targeting terpyridine iron(II) complexes for cellular imaging and remarkable photocytotoxicity. J Inorg Biochem. 116:77-87. 2012..PMID:23022691

Khan I, Kumar N, Narra S, Kondaiah P*. Activation of TGF-beta pathway by areca nut constituents: A possible cause of Oral submucous fibrosis. PLoS One. 7(12):e51806. 2012.PMID:23284772

Munoz-Ubeda M, Misra SK,, Barran-Berdon, A, DattaS, Aicart-Ramos C, Castro-Hartmann P, Kondaiah P, Junquera E, Bhattacharya S and Aicart E. How Does Spacer Length of Cationic Gemini Lipids Influence the Lipoplex Formation with Plasmid DNA? Physicochemical and Biochemical Characterizations and their Relevance in Gene Therapy. Biomacromolecules; 13(12):3926-37. 2012.PMID: 23130552

Prasad P, Khan I, Sasmal PK, Koley D, Kondaiah P, Chakravarty AR. Planar triazinium cations from vanadyl-mediated ring cyclizations: the thiazole species for efficient nuclear staining and photocytotoxicity. Dalton Trans. 42(13):4436-49, 2013. PMID: 23360958

Arimappamagan A, Somasundaram K, Thennarasu K, Peddagangannagari S, Srinivasan H, Shailaja BC, Samuel C, Patric IR, Shukla S, Thota B, Prasanna KV, Pandey P, Balasubramaniam A, Santosh V, Chandramouli BA, Hegde AS, Kondaiah P, Sathyanarayana Rao MR. A fourteen gene GBM prognostic signature identifies association of immune response pathway and mesenchymal subtype with high risk group. PLoS ONE 8(4): e62042. doi:10.1371. 2013.PMID:23646114

Metri PK, Naz S, Kondaiah P* and Prasad KR. MPK-09, a small molecule inspired from bio-active styryllactone restores the wild type function of mutant p53. ACS Chem. Biol. 8 (7). pp. 1429-1434 2013. PMID: 23621494

Sehgal P, Kumar N, Praveen Kumar VR, Patil S, Bhattacharya A, Vijaykumar M, Mukherjee G, Kondaiah P*. Regulation of protumorigenic pathways by Insulin like growth factor binding protein2 and its association along with ?-catenin in breast cancer lymph node metastasis. Mol Cancer. 12(1):63, 2013.PMID: 23767917

Swapna M, Premakumari C, Reddy SN, Padmaja A, Padmavathi V, Kondaiah P, Krishna NS. Synthesis, antimicrobial and cytotoxic activities of sulfonamidomethane linked heterocycles. Chem Pharm Bull (Tokyo). 2013;61(7):722-30. 2013. PMID: 23812397

Misra SK, Biswas J, Kondaiah P, Bhattacharya S. Gene transfection in high serum levels: case studies with new cholesterol based cationic gemini lipids. PLoS One. Jul 4;8(7):e68305. doi: 10.1371. 2013.PMID:23861884

Naz S, Bashir M, Ranganathan P, Bodapati P, Santosh V and Kondaiah P*. Pro tumorigenic actions of S100A2 involves regulation of PI3/Akt signaling and functional interaction with Smad3. Carcinogenesis. 35(1):14-23. 2013.PMID:23996929

Misra SK, Muñoz-Úbeda M, Datta S, Barrán-Berdón AL, Aicart-Ramos C, Castro-Hartmann P, Kondaiah P, Junquera E, Bhattacharya S, Aicart E. Effects of a Delocalizable Cation on the Headgroup of Gemini Lipids on the Lipoplex-Type Nanoaggregates Directly Formed from Plasmid DNA. Biomacromolecules. 2013 Oct 15. PMID:24083552

Mitra K, Basu U, Khan I, Maity B, Kondaiah P, Chakravarty AR. Remarkable anticancer activity of ferrocenyl-terpyridine platinum(ii) complexes in visible light with low dark toxicity. Dalton Trans. 4;43(2):751-63. doi: 10.1039/c3dt51922h. 2013.PMID: 24149439

Prasad P, Khan I, Kondaiah P, Chakravarty AR. Mitochondria-Targeting Oxidovanadium(IV) Complex as a Near-IR Light Photocytotoxic Agent. Chemistry. 16;19(51):17445-55. 2013.PMID: 24227284

Misra SK, Naz S, Kondaiah P, Bhattacharya S. A cationic cholesterol based nanocarrier for the delivery of p53-EGFP-C3 plasmid to cancer cells. Biomaterials. Jan;35(4):1334-46. doi: 10.1016/j. 2014. PMID:24211075

Moitra P, Kumar K, Kondaiah P, Bhattacharya S. Efficacious Anticancer Drug Delivery Mediated by a pH-Sensitive Self-Assembly of a Conserved Tripeptide Derived from Tyrosine Kinase NGF Receptor. Angew Chem Int Ed Engl. 20;53(4):1113-7. 2014 PMID: 24338837

Praveen Kumar VR, Sehgal P, Thota B, Patil S, Santosh V, Kondaiah P*. Insulin like growth factor binding protein4 (IGFBP4) promotes malignant Glioma progression and regulates key factors involved in EMT and invasion. J. Neuro Oncol. 116:455–464. 2014.PMID:24395346

Basu U, Khan I, Hussain A, Gole B, Kondaiah P, Chakravarty AR Carbohydrate-Appended Tumor Targeting Iron(III) Complexes Showing Photocytotoxicity in Red Light. Inorg Chem. Feb 17; 53 (4):2152-62. 2014.PMID: 24467402

Reddy PR, Reddy GM, Padmaja A, Padmavathi V, Kondaiah P, Krishna NS. Synthesis, antioxidant, and cytotoxic activities of N-azole substituted thiomorpholine derivatives. Arch Pharm (Weinheim) 347(3):221-8. 2014. PMID: 24395622

Rao SA, Srinivasan S, Patric IR, Hegde AS, Chandramouli BA, Arimappamagan A, Santosh V, Kondaiah P, Rao MR, Somasundaram K. A 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma. PLoS One. 24;9(1):e85200. 2014.PMID: 24475040

Rotti H, Guruprasad KP, Nayak J, Kabekkodu SP, Kukreja H, Mallya S, Nayak J, Bhradwaj RC, Gangadharan GG, Prasanna BV, Raval R, Kamath A, Gopinath PM, Kondaiah P, Satyamoorthy K.: Immunophenotyping of normal individuals classified on the basis of human dosha prakriti. J Ayurveda Integr Med. Jan;5(1):43-9. 2014.PMID: 24812475

Prasad P, Pant I, Khan I, Kondaiah P* and Chakravarty AR*. Mitochondria-Targeted Photoinduced Anticancer Activity of Oxidovanadium(IV) Complexes of Curcumin in Visible Light. Eur. J. Inorg. Chem. 2014 (In press)

Thota B, Arimappamagan A, Thennarasu K, Shastry AH, Pandey P, Chandramouli BA, Hegde AS, Kondaiah P* and Santosh V*.STAT-1 expression is regulated by IGFBP-3 in malignant glioma cells and is a strong predictor of poor survival in glioblastoma patients. J. Neurosurgery, 2014.PMID: 24878287

Basu U, Pant I, Khan I, Hussain A, Kondaiah P, Chakravarty AR . Iron(III) Catecholates for Cellular Imaging and Photocytotoxicity in Red Light. Chem Asian J. 2014 Jul 14. .PMID: 25044734

Rotti H, Raval R, Anchan S, Bellampalli R, Bhale S, Bharadwaj R, Bhat BK, Dedge AP, Dhumal VR, Gangadharan GG, Girijakumari TK, Gopinath PM, Govindaraj P, Halder S, Joshi KS, Kabekkodu SP, Kamath A, Kondaiah P, Kukreja H, Kumar KL, Nair S, Nair SN, Nayak J, Prasanna BV, Rashmishree M, Sharanprasad K, Thangaraj K, Patwardhan B, Satyamoorthy K, Valiathan MV. Determinants of prakriti, the human constitution types of Indian traditional medicine and its correlation with contemporary science. J Ayurveda Integr Med. 2014 Jul;5(3):167-75. PMID: 25336848

Kumar K, Maiti B, Kondaiah P, Bhattacharya S: Efficacious Gene Silencing in Serum and Significant Apoptotic Activity Induction by Survivin Downregulation Mediated by New Cationic Gemini Tocopheryl Lipids. Mol Pharm. 2014.[Epub ahead of print]

Patents

US and European patent filed (awaiting final approval); Indian Patent already filed. Title: Method for diagnosis of Glioma: Distinguishing between progressive and de novo types Inventers: Kumaravel Somasundaram, Alangar Sathyaranjandas Hegde, Sridevi Hegde, Paturu Kondaiah, and Manchanahalli Rangaswamy Satyanarayana Rao

Indian patent filed; US patent and European patent to be filed. Title: Molecular markers for identification of Astrocytoma, its grades and glioma prognosis Inventers: Kumaravel Somasundaram, Alangar Sathyaranjandas Hegde, Sridevi Hegde, Paturu Kondaiah, and Manchanahalli Rangaswamy Satyanarayana Rao

Indian patent filed; US patent and European patent to be filed. Title: Secreted and Plasma Membrane Associated Biomarkers for the Diagnosis of Higher- and Lower-Grade Astrocytoma Inventers: Kumaravel Somasundaram, Alangar Sathyaranjandas Hegde, Sridevi Hegde, Paturu Kondaiah, Manchanahalli Rangaswamy Satyanarayana Rao and Vani Santosh

Provisional patent filed; US patent and European patent to be filed Title: TOP2A inhibition by temozolomide and its predictive value of GBM patient’s survival. Inventors: Kumaravel Somasundaram, Arivazhagan A, Kandavel Thennarasu, Alangar Sathyaranjandas Hegde, Ashwathnarayana Rao Chandramouli, Vani Santosh, Paturu Kondaiah, Manchanahalli Rangaswamy Satyanarayana Rao.

Indian Provisional patent filed (Application No. 1728/CHE/2013) Title: Compounds for activation of mutant p53 protein and process thereof. Inventors: Kavirayani Prasad, Paturu Kondaiah, Prashant Metri, Sarwat Naz.